Linked Life Data

8808769

Source:http://linkedlifedata.com/resource/pubmed/id/8808769

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-1-22
pubmed:abstractText
A single type of high density lipoprotein (HDLp) binding sites is present at intact fat body tissue and in fat body membranes of larval and adult locusts. HDLp is bound with high affinity (Kd approximately 10(-7) M). This interaction does not require divalent cations and is heat-labile because heat-treatment of fat body membranes results in a substantial reduction of the maximal binding capacity. In addition to unlabeled HDLp and low density lipophorin (LDLp), human low density lipoprotein also seems to compete with radiolabeled HDLp for this binding site, suggesting a relaxed specificity. Induction of lipid mobilization with adipokinetic hormone did not change the binding characteristics of the fat body. An increase in the binding capacity of intact fat body tissue in the adult stage suggests that the number of cell surface binding sites is upregulated during development. However, the total number of HDLp binding sites appears to be constant, because larval and adult fat body membranes have similar binding capacities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-2275
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1345-55
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Interaction of an insect lipoprotein with its binding site at the fat body.
pubmed:affiliation
Department of Experimental Zoology, Utrecht University, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't