Linked Life Data

8799932

Source:http://linkedlifedata.com/resource/pubmed/id/8799932

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-11-7
pubmed:abstractText
We describe the necropsy results from three common marmosets presented during an outbreak of hemorrhagic diarrhea in a colony of 230 common marmosets (Callithrix jacchus). Necropsy revealed consistent hemorrhagic typhlocolitis and variable ileitis associated with gram-negative bacilli closely adherent to enterocytes. Electron microscopy revealed bacilli attached intimately to shallow cup-like projections of enterocyte apical membranes with loss of microvilli (attaching and effacing). Escherichia coli isolates from affected marmosets were serogroup O26 and were positive for the E. coli attaching and effacing locus and negative for shiga-like toxin I and II, heat-stable enterotoxins a and b, and heat-labile enterotoxin by DNA probe hybridization. Results of a Vero cell cytotoxicity assay confirmed that the E. coli isolates did not produce shiga-like toxin. The increased availability of diagnostic probes for specific virulence factors such as attaching and effacing E. coli should lead to a greater understanding of the frequency of E. coli as a cause of diarrhea in nonhuman primates.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0023-6764
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
275-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Hemorrhagic typhlocolitis associated with attaching and effacing Escherichia coli in common marmosets.
pubmed:affiliation
Wisconsin Regional Primate Research Center, University of Wisconsin, Madison 53715-1299, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.