|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1996-10-28
|
|
pubmed:abstractText |
Addison's disease is mainly caused by autoimmune destruction of the steroid-producing cells in the adrenal glands. Key enzymes in steroid biosynthesis have been implicated as the major targets of autoantibodies in this disease. The study of B-cell-dependent autoimmune responses reveals two distinguishable forms of Addison's disease. This should permit very accurate diagnosis of the disease and increase future prospects of disease prevention.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1357-4310
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
2
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
282-9
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:8796908-Addison Disease,
pubmed-meshheading:8796908-Adrenal Cortex,
pubmed-meshheading:8796908-Autoantibodies,
pubmed-meshheading:8796908-Autoantigens,
pubmed-meshheading:8796908-Autoimmunity,
pubmed-meshheading:8796908-B-Lymphocytes,
pubmed-meshheading:8796908-Female,
pubmed-meshheading:8796908-Humans,
pubmed-meshheading:8796908-Major Histocompatibility Complex,
pubmed-meshheading:8796908-Male,
pubmed-meshheading:8796908-Polyendocrinopathies, Autoimmune,
pubmed-meshheading:8796908-Steroids,
pubmed-meshheading:8796908-T-Lymphocytes
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
The autoimmune basis of adrenocortical destruction in Addison's disease.
|
|
pubmed:affiliation |
Department of Internal Medicine, University Hospital, Uppsala University, Sweden. ola.winqvist@medicin.uu.se
|
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|
