Linked Life Data

8793775

Source:http://linkedlifedata.com/resource/pubmed/id/8793775

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-12-10
pubmed:abstractText
The effect of OP-1206, a prostaglandin E1 derivative, on cauda equina function was analyzed in a model for acute cauda equina compression in the dog. An inflatable balloon was placed under the lamina of the seventh lumbar vertebra in the dog and muscle action potential area (MAP area) and nerve-conduction velocity (NCV) were monitored during 2 h of compression and 1.5 h of recovery. OP-1206 was infused systemically at three concentrations. Only the highest concentration (30 ng/kg/min) of OP-1206 could prevent the reduction in NCV. However, this concentration had no similar effect on the MAP area. The data suggest the potential therapeutic use of prostaglandin E1 analogues for the future treatment of intermittent claudication.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0895-0385
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Effects of OP-1206 (prostaglandin E1) on nerve-conduction velocity in the dog cauda equina subjected to acute experimental compression.
pubmed:affiliation
Department of Orthopaedic Surgery, Fukushima Medical College, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't