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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1996-11-20
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pubmed:abstractText |
During the past decade, gastro-oesophageal reflux disease has been shown to be the most common identifiable cause of non-cardiac chest pain of oesophageal origin. The development of combined pH-pressures recording systems has also contributed to a better understanding of the underlying mechanisms of pain perception. Beside typical gastro-oesophageal reflux disease, many patients with non-cardiac chest pain appear to have an hypersensitivity to acid or mechanical stimuli, or both. Despite new insights into the pathophysiology of gastro-oesophageal reflux disease, therapy is limited to the suppression of noxious stimuli by antisecretory drugs or surgery. New therapeutic approaches using drugs affecting visceral perception, and well-controlled placebo trials are urgently needed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0954-691X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1152-9
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pubmed:dateRevised |
2009-10-16
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pubmed:meshHeading |
pubmed-meshheading:8789304-Chest Pain,
pubmed-meshheading:8789304-Esophagus,
pubmed-meshheading:8789304-Gastric Acid,
pubmed-meshheading:8789304-Gastroesophageal Reflux,
pubmed-meshheading:8789304-Humans,
pubmed-meshheading:8789304-Hydrogen-Ion Concentration,
pubmed-meshheading:8789304-Monitoring, Physiologic
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pubmed:year |
1995
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pubmed:articleTitle |
Oesophageal sensitivity to acid in patients with non-cardiac chest pain: is the oesophagus hypersensitive?
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, University of Nantes, France.
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pubmed:publicationType |
Journal Article,
Review
|