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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-8-25
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pubmed:abstractText |
The tightness of the ureterovesical junction depends on all the structures composing the terminal and intra-mural ureter. The muscular, collagenic, and elastic fibers of the ureter constitute a mesh net which is stretched during bladder distention and closes the ureteric orifice as a valve. Congenital vesico-ureteric reflux results from a primary structural insufficiency of the terminal ureter or insufficiency of the bladder wall backing. As embryology shows primary reflux can be caused by a high ectopic implantation of the ureter. It results from the development of an ureteric bud appearing in a lower than normal position on the Wolffian duct. This results in a higher and more lateral opening of the ureteric orifice in the bladder which leads to a shorter intra-mural tunnel predisposing it to reflux. Secondary or acquired refluxes are associated with chronic obstructions (i.e. neurogenic bladder--lower urinary tract obstruction), and inflammatory lesions. Their pathogeneses are described and discussed. The maturation of the ureterovesical junction is considered a mechanism involving a reduced likelihood of secondary reflux. It may also, during the first years of life, palliate some minimal structural deficiencies of the intra-mural ureter, but growth and development are unlikely to normalize an ureter presenting at birth with a severe constitutional anomaly.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0340-2592
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
118-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:878105-Adolescent,
pubmed-meshheading:878105-Adult,
pubmed-meshheading:878105-Age Factors,
pubmed-meshheading:878105-Child,
pubmed-meshheading:878105-Child, Preschool,
pubmed-meshheading:878105-Female,
pubmed-meshheading:878105-Hernia, Hiatal,
pubmed-meshheading:878105-Humans,
pubmed-meshheading:878105-Infant,
pubmed-meshheading:878105-Infant, Newborn,
pubmed-meshheading:878105-Pregnancy,
pubmed-meshheading:878105-Ureter,
pubmed-meshheading:878105-Ureteral Obstruction,
pubmed-meshheading:878105-Urinary Bladder,
pubmed-meshheading:878105-Vesico-Ureteral Reflux
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pubmed:year |
1977
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pubmed:articleTitle |
[The physiopathology of vesicoureteral reflux (author's transl)].
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pubmed:publicationType |
Journal Article,
English Abstract
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