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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1996-10-11
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pubmed:abstractText |
Ovine lymphocyte antigen is associated with reduced faecal egg counts in 4-month-old lambs following natural, predominantly Ostertagia circumcincta infection. International Journal for Parasitology 26: 423-428. Ten lymphocyte antigens were defined in a flock of Scottish Blackface sheep known to be naturally exposed to infection with Ostertagia circumcincta. Population and family studies suggested that the 10 antigens were products of class I loci. Antigen G13br was in linkage disequilibrium with allele g2 at the DRB1 locus. The g2 allele has previously been associated with reduced faecal egg counts in a different crop of lambs from the same farm. In this study antigen G13br was also associated with a reduction in faecal egg counts. The results provide partial confirmation of the role of the major histocompatibility complex in resistance to natural, predominantly O. circumcincta infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0020-7519
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
423-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8773530-Alleles,
pubmed-meshheading:8773530-Animals,
pubmed-meshheading:8773530-Feces,
pubmed-meshheading:8773530-Female,
pubmed-meshheading:8773530-Gene Deletion,
pubmed-meshheading:8773530-Genetic Markers,
pubmed-meshheading:8773530-HLA-DR Antigens,
pubmed-meshheading:8773530-HLA-DRB1 Chains,
pubmed-meshheading:8773530-Histocompatibility Antigens Class I,
pubmed-meshheading:8773530-Linkage Disequilibrium,
pubmed-meshheading:8773530-Lymphocytes,
pubmed-meshheading:8773530-Major Histocompatibility Complex,
pubmed-meshheading:8773530-Ostertagia,
pubmed-meshheading:8773530-Ostertagiasis,
pubmed-meshheading:8773530-Parasite Egg Count,
pubmed-meshheading:8773530-Sheep,
pubmed-meshheading:8773530-Sheep Diseases
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pubmed:year |
1996
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pubmed:articleTitle |
An ovine lymphocyte antigen is associated with reduced faecal egg counts in four-month-old lambs following natural, predominantly Ostertagia circumcincta infection.
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pubmed:affiliation |
Glasgow University Veterinary School, Scotland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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