pubmed-article:8750651 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8750651 | lifeskim:mentions | umls-concept:C0138741 | lld:lifeskim |
pubmed-article:8750651 | lifeskim:mentions | umls-concept:C1366489 | lld:lifeskim |
pubmed-article:8750651 | lifeskim:mentions | umls-concept:C1417779 | lld:lifeskim |
pubmed-article:8750651 | lifeskim:mentions | umls-concept:C1510438 | lld:lifeskim |
pubmed-article:8750651 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:8750651 | pubmed:dateCreated | 1996-10-11 | lld:pubmed |
pubmed-article:8750651 | pubmed:abstractText | The ultrasensitive PSA assay has been recently acknowledged as a useful tool for the monitoring of patients prostatectomized for prostatic cancer. We have evaluated a commercially available ultrasensitive PSA assay (Immulite Third Generation PSA-DPC-Los Angeles CA) in comparison with the routinely used PSA (Immulite PSA-DPC-Los Angeles CA). When evaluated with different approaches, the analytical sensitivity of ultrasensitive PSA ranged between 0.0029 and 0.0038 ng/ml. The biological detection limit was 0.0098 ng/ml. Dilution of samples with low PSA levels showed a good recovery (from 88 to 113%) up to 1:128 dilution factor (final PSA levels ranging from 0.004 to 0.016 ng/ml in different samples). The assay precision was excellent in the low dose range, the highest interassay interadjustment CV among replicates being 5.84% when assaying serum samples with PSA lower than 1.0 ng/ml. Besides its role in the follow-up of prostatectomized patients, the evaluated ultrasensitive PSA could be reliably used for the detection of clinically meaningful PSA variations in the low dose range, and it could therefore be a candidate for the assessment of PSA velocity. | lld:pubmed |
pubmed-article:8750651 | pubmed:language | eng | lld:pubmed |
pubmed-article:8750651 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8750651 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8750651 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8750651 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8750651 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8750651 | pubmed:issn | 0393-6155 | lld:pubmed |
pubmed-article:8750651 | pubmed:author | pubmed-author:LeonAA | lld:pubmed |
pubmed-article:8750651 | pubmed:author | pubmed-author:GionMM | lld:pubmed |
pubmed-article:8750651 | pubmed:author | pubmed-author:MioniVV | lld:pubmed |
pubmed-article:8750651 | pubmed:author | pubmed-author:BarichelloMM | lld:pubmed |
pubmed-article:8750651 | pubmed:author | pubmed-author:BarioliPP | lld:pubmed |
pubmed-article:8750651 | pubmed:author | pubmed-author:SartorelloPP | lld:pubmed |
pubmed-article:8750651 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8750651 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:8750651 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8750651 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8750651 | pubmed:pagination | 229-33 | lld:pubmed |
pubmed-article:8750651 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:8750651 | pubmed:articleTitle | Third-generation PSA: ultrasensitive or ultraprecise assay? | lld:pubmed |
pubmed-article:8750651 | pubmed:affiliation | Center for the Study of Biological Markers of Malignancy, National Center for the Application of Biotechnologies in Oncology, Venezia, Italy. | lld:pubmed |
pubmed-article:8750651 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8750651 | pubmed:publicationType | Comparative Study | lld:pubmed |