Linked Life Data

8747219

Source:http://linkedlifedata.com/resource/pubmed/id/8747219

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1996-10-9
pubmed:abstractText
The serotonergic system of the medicinal leech comprises a small number of iterated, identified neurons, of which the Retzius (Rz) neurons are major components. Activity in pressure mechanosensory (P) cells sufficient to elicit locomotory and defensive behaviors also excites Rz neurons. We characterized the interactions between P and Rz neurons within the ganglion and at different distances along the nerve cord. 2. Within a ganglion 1) P cells excited both Rz neurons, electrically close to the site of electrical coupling between the Rz neurons; 2) each of the four P cells had similar effects on the Rz neurons; and 3) homologous contralateral P cells shared interneuronal pathways. These data show that P cells provide nearly identical bilateral information onto Rz neurons. 3. Along the nerve cord 1) every P cell excited Rz neurons in ganglia anterior and posterior to the site of stimulation; 2) the signal was carried the entire length of the nerve cord along interneuronal pathways with similar overall (but regionally different) conduction velocities in the two directions; 3) the amplitude of the Rz responses was smaller as the distance to the activated P cell increased; 4) the rate of change of the amplitude along the cord was larger when the signal traveled from front-to-back than in the opposite direction. 4. These data shows that mechanosensory input from any segment could excite Rz neurons along the cord, in proportion to the intensity of the stimulus.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-3077
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2614-24
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Widespread mechanosensory activation of the serotonergic system of the medicinal leech.
pubmed:affiliation
Department of Biology, University of California, San Diego, La Jolla 92093-0357, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't