Linked Life Data

873734

Source:http://linkedlifedata.com/resource/pubmed/id/873734

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-9-2
pubmed:abstractText
Using two immunogenic methylcholanthrene-induced fibrosarcomas in CD2F1 male mice, initial observations suggested that the rate of tumor growth might be enhanced by castration. For confirmation, tumor transplantation experiments using more than 500 mice were carried out in order to compare tumor specific transplantation immunity in castrate and in control male mice. Inbred mice bearing a 3-methylcholanthrene-induced fibrosarcoma transplant underwent surgical excision of the tumor; and specific resistance to subsequent challenges using varying doses of that tumor cell line were compared in castrate and in noncastrate groups of mice. Although castration influenced the rate of tumor growth, castration had no apparent effect on tumor specific immunoresistance. Mechanisms of host-tumor immunorelationships are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0021-0005
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-38
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Castration effects on tumor specific immunity.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.