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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1996-10-24
|
| pubmed:abstractText |
The head-associated lymphoid tissues of the chicken, composed of the harderian gland and the conjunctiva-associated lymphoid tissue (CALT), were studied to determine whether changes occurred in lymphocyte subpopulations as chickens age from 1 week to 8 weeks. The B cells and subpopulations of T-lymphocytes of the head-associated lymphoid tissues were identified using in situ immunohistochemical staining. Monoclonal antibodies specific for various lymphocyte surface antigens were used. The concentration of T-lymphocytes, particularly CD3+ and CD4+ cells, within the harderian gland increased with age, whereas the concentration of B cells remained the same. B-lymphocytes were observed within the germinal centers of the CALT of 4-week-old birds. The T-lymphocytes within the CALT surrounded the B-cell-rich germinal centers. CD3+ T-lymphocytes were the predominant cell population in all age groups examined. Increasing concentrations of CD3+, CD4+, and CD8+ T-lymphocytes were observed within the CALT as chicks developed from 1 week to 4 weeks of age. Finally, no changes were observed in lymphocyte populations within the CALT as chicks developed from 4 weeks to 8 weeks of age.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0005-2086
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
39
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
736-42
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8719207-Aging,
pubmed-meshheading:8719207-Animals,
pubmed-meshheading:8719207-Antibodies, Monoclonal,
pubmed-meshheading:8719207-Antigens, CD3,
pubmed-meshheading:8719207-B-Lymphocyte Subsets,
pubmed-meshheading:8719207-Biological Markers,
pubmed-meshheading:8719207-Brain,
pubmed-meshheading:8719207-CD4-Positive T-Lymphocytes,
pubmed-meshheading:8719207-CD8-Positive T-Lymphocytes,
pubmed-meshheading:8719207-Chickens,
pubmed-meshheading:8719207-Conjunctiva,
pubmed-meshheading:8719207-Female,
pubmed-meshheading:8719207-Harderian Gland,
pubmed-meshheading:8719207-Head,
pubmed-meshheading:8719207-Housing, Animal,
pubmed-meshheading:8719207-Lymphoid Tissue,
pubmed-meshheading:8719207-Male,
pubmed-meshheading:8719207-Specific Pathogen-Free Organisms,
pubmed-meshheading:8719207-Spleen,
pubmed-meshheading:8719207-T-Lymphocyte Subsets
|
| pubmed:articleTitle |
B cells and T-lymphocyte subsets of the head-associated lymphoid tissues of the chicken.
|
| pubmed:affiliation |
Department of Microbiology, Immunology, and Preventive Medicine, Iowa State University, Ames 50011, USA.
|
| pubmed:publicationType |
Journal Article
|