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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-9-12
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pubmed:abstractText |
The human gastric mucosa contains five isozymogens of pepsinogen (pepsinogens PGA1-PGA5), two isozymogens of gastricsinogen (gastricsinogens PGC6-PGC7) and zymogens of cathepsins. Ratios between some individual pepsins or pepsinogens are very important from a diagnostic point of view. The ratio of pepsinogen 3 to pepsinogen 5 is significant marker of gastric cancer and gastric ulcer. High-performance ion-exchange chromatography is an easy and fast method for determination of ratios between individual proteolytic zymogens in human gastric mucosa and thus could serve for additional diagnosis of gastric diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5327
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-42
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:8711409-Animals,
pubmed-meshheading:8711409-Chromatography, High Pressure Liquid,
pubmed-meshheading:8711409-Gastric Mucosa,
pubmed-meshheading:8711409-Humans,
pubmed-meshheading:8711409-Pepsin A,
pubmed-meshheading:8711409-Pepsinogens,
pubmed-meshheading:8711409-Stomach Ulcer,
pubmed-meshheading:8711409-Swine
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pubmed:year |
1996
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pubmed:articleTitle |
High performance liquid chromatography enables fast determination of ratios between individual proteolytic enzymes in human gastric mucosa.
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pubmed:affiliation |
Department of Biochemistry and Microbiology, 1st Faculty of Medicine, Charles University; Prague, Czech Republic.
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pubmed:publicationType |
Journal Article
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