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rdf:type |
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lifeskim:mentions |
umls-concept:C0009264,
umls-concept:C0014563,
umls-concept:C0016986,
umls-concept:C0022885,
umls-concept:C0028351,
umls-concept:C0030685,
umls-concept:C0030705,
umls-concept:C0039593,
umls-concept:C0040059,
umls-concept:C0234402,
umls-concept:C0391871,
umls-concept:C0441889,
umls-concept:C0599756,
umls-concept:C0680255,
umls-concept:C1280500,
umls-concept:C1283071,
umls-concept:C1956346,
umls-concept:C1963578
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pubmed:issue |
1-2
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|
pubmed:dateCreated |
1996-8-7
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pubmed:abstractText |
We investigated the effect of gallopamil administration during a cold pressor test (CPT) in 18 patients suffering from chronic angina (CA) and in 21 healthy subjects. CA patients showed increased basal levels of beta-thromboglobulin and thromboxane B2 compared to control patients and normal plasma levels of catecholamines. CPT caused plasma catecholamines, beta-thromboglobulin and TxB2 levels to rise. This rise was greater in CA patients than in control patients. Administration of gallopamil (50 mg kg-1 three times a day for 30 days) reduced plasma levels of catecholamines, beta-thromboglobulin and TxB2 blood concentrations either under basal conditions or after CPT. Our data suggest that gallopamil is able to modulate the response induced by adrenergic stress.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1043-6618
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
49-55
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8668647-Adult,
pubmed-meshheading:8668647-Aged,
pubmed-meshheading:8668647-Angina Pectoris,
pubmed-meshheading:8668647-Calcium Channel Blockers,
pubmed-meshheading:8668647-Cold Temperature,
pubmed-meshheading:8668647-Coronary Disease,
pubmed-meshheading:8668647-Epinephrine,
pubmed-meshheading:8668647-Female,
pubmed-meshheading:8668647-Gallopamil,
pubmed-meshheading:8668647-Humans,
pubmed-meshheading:8668647-Male,
pubmed-meshheading:8668647-Middle Aged,
pubmed-meshheading:8668647-Norepinephrine,
pubmed-meshheading:8668647-Thromboxane B2,
pubmed-meshheading:8668647-beta-Thromboglobulin
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pubmed:articleTitle |
Effects of gallopamil on epinephrine and norepinephrine plasmatic levels and on TxB2 and beta-tg release in patients with coronary artery disease during adrenergic stimulus with cold pressor test.
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pubmed:affiliation |
Department of Internal Medicine and Medical Therapeutics, University of Messina, Italy.
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pubmed:publicationType |
Journal Article
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