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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1996-8-8
|
| pubmed:abstractText |
Conjugation chemistry and kit formulated binding of the NHS ester of 6-(4'-(4"-carboxyphenoxy)butyl)-2, 10-dimercapto-2,10-dimethyl-4,8-diazaundecane (NHS-BAT ester) to monoclonal antibodies (MAbs) was investigated. The functionalities of the resulting BAT conjugated and 99mTc-labeled MAbs BW 431/26, MAb 425 and bispecific MDX210 (fragment construct) were tested by immunoreactivity and immunoscintigraphy.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0161-5505
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
37
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
362-70
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8667077-Animals,
pubmed-meshheading:8667077-Humans,
pubmed-meshheading:8667077-Isotope Labeling,
pubmed-meshheading:8667077-Mercaptoethylamines,
pubmed-meshheading:8667077-Radioimmunodetection,
pubmed-meshheading:8667077-Rats,
pubmed-meshheading:8667077-Rats, Sprague-Dawley,
pubmed-meshheading:8667077-Reagent Kits, Diagnostic,
pubmed-meshheading:8667077-Succinimides,
pubmed-meshheading:8667077-Technetium,
pubmed-meshheading:8667077-Tissue Distribution
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Bifunctional NHS-BAT ester for antibody conjugation and stable technetium-99m labeling: conjugation chemistry, immunoreactivity and kit formulation.
|
| pubmed:affiliation |
Department of Nuclear Medicine, University of Heidelberg, Germany.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|