|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1996-7-15
|
|
pubmed:abstractText |
RNA was specifically extracted from tumor and peritumor tissue of a hepatitis C virus (HCV)-associated hepatocellular carcinoma after microdissection. RT-PCR products of the HCV 5'-noncoding (NC), core and nonstructural (NS)-5 gene were examined. Nucleotide sequences of the core region derived from the tumor tissue revealed deletions and mutations resulting in truncated proteins. Peritumor and serum HCV sequences were unaffected.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0006-291X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
27
|
|
pubmed:volume |
219
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
911-5
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:8645278-Amino Acid Sequence,
pubmed-meshheading:8645278-Base Sequence,
pubmed-meshheading:8645278-Carcinoma, Hepatocellular,
pubmed-meshheading:8645278-DNA Primers,
pubmed-meshheading:8645278-Genes, Viral,
pubmed-meshheading:8645278-Hepacivirus,
pubmed-meshheading:8645278-Humans,
pubmed-meshheading:8645278-Liver Neoplasms,
pubmed-meshheading:8645278-Male,
pubmed-meshheading:8645278-Middle Aged,
pubmed-meshheading:8645278-Molecular Sequence Data,
pubmed-meshheading:8645278-Mutation,
pubmed-meshheading:8645278-Polymerase Chain Reaction,
pubmed-meshheading:8645278-RNA, Viral,
pubmed-meshheading:8645278-Sequence Deletion,
pubmed-meshheading:8645278-Viral Core Proteins,
pubmed-meshheading:8645278-Viral Nonstructural Proteins
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Hepatitis C virus sequences encoding truncated core proteins detected in a hepatocellular carcinoma.
|
|
pubmed:affiliation |
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus, Frankfurt a. M., Germany.
|
|
pubmed:publicationType |
Journal Article,
Case Reports
|
