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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-7-29
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pubmed:abstractText |
Administration of vasopressin (0.4 units/minute) via the superior mesenteric artery (SMA) resulted in a mean 25% reduction in corrected hepatic venous wedge pressure (CHWP) in 9 stable non-bleeding patients with cirrhosis and portal hypertension. There was wide variation of response in individual patients with two of nine showing no decrease in CHWP to vasopressin. Selective intra-arterial infusion did not protect against the systemic effects of vasopressin and resulted in significant elevations in blood pressure (21%) and systemic vascular resistance (39%). A slight decrease in cardiac output (11%) was also observed. In 6 of these patients, vasopressin (0.4 units/minute) was also given intravenously. The resultant decreases in CHWP were similar to those observed with SMA administration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0020-9996
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
210-4
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:863624-Alcoholism,
pubmed-meshheading:863624-Female,
pubmed-meshheading:863624-Hepatic Veins,
pubmed-meshheading:863624-Humans,
pubmed-meshheading:863624-Hypertension, Portal,
pubmed-meshheading:863624-Injections, Intra-Arterial,
pubmed-meshheading:863624-Injections, Intravenous,
pubmed-meshheading:863624-Liver Cirrhosis,
pubmed-meshheading:863624-Male,
pubmed-meshheading:863624-Mesenteric Arteries,
pubmed-meshheading:863624-Vasopressins,
pubmed-meshheading:863624-Venous Pressure
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pubmed:articleTitle |
Hemodynamic effects of superior mesenteric arterial and intravenous vasopressin infusions in patients with portal hypertension.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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