rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1996-6-17
|
pubmed:abstractText |
Prior studies suggest that fetal plasma cholesterol is regulated in part by the rate of uptake and utilization of low-density lipoprotein cholesterol by the fetal adrenals for use in steroid biosynthesis. Direct evidence for this phenomenon and the kinetics of this process is, however, virtually impossible to obtain in a controlled experiment in the developing human. In the current study we sought to take advantage of the anticipated transient inhibition of the hypothalamic-pituitary-adrenal axis that occurs after antenatal therapy with glucocorticosteroids, to evaluate the temporal relationship between fetal adrenal steroids and plasma lipoprotein cholesterol levels in umbilical cord blood at delivery.
|
pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0002-9378
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
174
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
562-5
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:8623785-Apolipoproteins B,
pubmed-meshheading:8623785-Betamethasone,
pubmed-meshheading:8623785-Cholesterol,
pubmed-meshheading:8623785-Dehydroepiandrosterone,
pubmed-meshheading:8623785-Dehydroepiandrosterone Sulfate,
pubmed-meshheading:8623785-Female,
pubmed-meshheading:8623785-Fetal Blood,
pubmed-meshheading:8623785-Fetal Organ Maturity,
pubmed-meshheading:8623785-Gestational Age,
pubmed-meshheading:8623785-Glucocorticoids,
pubmed-meshheading:8623785-Humans,
pubmed-meshheading:8623785-Hydrocortisone,
pubmed-meshheading:8623785-Infant, Newborn,
pubmed-meshheading:8623785-Lung,
pubmed-meshheading:8623785-Pregnancy
|
pubmed:year |
1996
|
pubmed:articleTitle |
Dynamics of the fetal adrenal, cholesterol, and apolipoprotein B responses to antenatal betamethasone therapy.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 35233-7333, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|