| pubmed-article:8606069 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0024518 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0206527 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0758434 | lld:lifeskim |
| pubmed-article:8606069 | lifeskim:mentions | umls-concept:C0758436 | lld:lifeskim |
| pubmed-article:8606069 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8606069 | pubmed:dateCreated | 1996-5-23 | lld:pubmed |
| pubmed-article:8606069 | pubmed:abstractText | Murine monoclonal antibodies (MAbs) specific for toxic shock syndrome toxin 1 (TSST-1), a bacterial superantigen, showed the ability either to detect TSST-1 bound to histocompatibility locus antigen (HLA)-DR molecules or to inhibit TSST-1 binding to HLA-DR. A MAb capable of detecting DR-bound TSST-1 could also inhibit the toxin-induced activation of a T-cell receptor Vbeta15-expressing murine T-cell hybridoma. Alternatively, MAbs with specificity for the HLA-DR association site could present TSST-1 in vitro, stimulating CD4+ human T cells to proliferate. These functional activities correlated directly with with MAb specificity for HLA-DR versus T-cell receptor Vbeta interaction sites on TSST-1 as determined by reactivity with a panel of recombinant TSST-1 mutant molecules. Therefore, these MAbs discriminate the superantigen functional sites on the TSST-1 molecule and constitute reagents with the property of being potent modulators of the toxic activity of TSST-1. | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8606069 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8606069 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8606069 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8606069 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:BrownEE | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:MatsumuraMM | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:KotzinB LBL | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:BoevMM | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:ShimonkevitzR... | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:HurleyJ MJM | lld:pubmed |
| pubmed-article:8606069 | pubmed:author | pubmed-author:MalmstromSS | lld:pubmed |
| pubmed-article:8606069 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8606069 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:8606069 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8606069 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8606069 | pubmed:pagination | 1133-9 | lld:pubmed |
| pubmed-article:8606069 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:meshHeading | pubmed-meshheading:8606069-... | lld:pubmed |
| pubmed-article:8606069 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8606069 | pubmed:articleTitle | Delineation by use of specific monoclonal antibodies of the T-cell receptor and major histocompatibility complex interaction sites on the superantigen toxic shock syndrome toxin 1. | lld:pubmed |
| pubmed-article:8606069 | pubmed:affiliation | Nexstar Pharmaceuticals, Inc., Lakewood Colorado, 80214, USA. | lld:pubmed |
| pubmed-article:8606069 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8606069 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8606069 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8606069 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8606069 | lld:pubmed |
