Linked Life Data

8582743

Source:http://linkedlifedata.com/resource/pubmed/id/8582743

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-3-19
pubmed:abstractText
Exercise generates free radicals and can cause damage to the tissues. This investigation shows the formation of ascorbate radicals during exercise training (ET) which reduce the toxicity of free radicals. Male Fischer-344 rats (n = 8) (77 weeks old) were given exercise training (ET) on a treadmill with a low intensity of exercise that gradually increased from the first to the ninth week resulting in an average increase in respiratory exchange ratio, oxygen consumption rate and heat production. The sedentary control (SC) rats (n = 8) were not exercised and maintained under the same conditions. The heart tissues from different SC and ET rats were analyzed for ascorbate free radical (Asc.-) using electron paramagnetic resonance (EPR). The heart tissue from the ET and not from the SC rat showed the presence of Asc.-. This Asc.- was characterized by an EPR spectrum which showed doublet with a hyperfine coupling constant of 1.89 Gauss (0.189 mT). The benefit of exercise could be attributed to the formation of ascorbate radical in the heart muscle of the old rat. Exercise training can provide protection to the heart tissue against oxidative damage via ascorbate ion and vitamin E.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0019-5499
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Exercise training generates ascorbate free radical in rat heart.
pubmed:affiliation
Department of Pharmacology, Southern Illinois University, School of Medicine, Springfield 62794-9230, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't