Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1977-6-30
|
| pubmed:abstractText |
The effects of gastrin on gastric acid secretion and on the incidence of gastric carcinoma induced by N-methyl-N'-nitro-N-nitrosoquanidine were investigated in rats. At Week 50 after the start of the experiment, it was found that prolonged administration of gastrin after treatment with N-methyl-N'-nitro-N-nitrosoquanidine resulted in a significant increase in gastric acid secretion and a significant reduction in the incidence of adenocarcinomas of the glandular stomach. The administration of gastrin did not influence the histological appearance of the few gastric adenocarcinomas that did develop.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0008-5472
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
37
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1808-10
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:858141-Adenocarcinoma,
pubmed-meshheading:858141-Animals,
pubmed-meshheading:858141-Drug Administration Schedule,
pubmed-meshheading:858141-Gastric Juice,
pubmed-meshheading:858141-Gastrins,
pubmed-meshheading:858141-Male,
pubmed-meshheading:858141-Methylnitronitrosoguanidine,
pubmed-meshheading:858141-Neoplasms, Experimental,
pubmed-meshheading:858141-Rats,
pubmed-meshheading:858141-Stomach Neoplasms
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Effect of prolonged administration of gastrin on experimental carcinogenesis in rat stomach induced by N-methyl-N' -nitro-N-nitrosoguanidine.
|
| pubmed:publicationType |
Journal Article
|