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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1996-3-13
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pubmed:abstractText |
The t(11;14)(q13;q32) is a chromosomal abnormality usually associated with mantle cell (centrocytic) lymphomas, although it has occasionally been reported in other chronic lymphoproliferative disorders such as chronic lymphocytic leukemia, prolymphocytic leukemia, splenic lymphoma with villous lymphocytes, and multiple myeloma. This abnormality results in the translocation of the bcl-1 oncogene from chromosome 11 to the immunoglobulin heavy chain locus on chromosome 14. The bcl-1 oncogene is a member of the cyclin gene family, and high levels of cyclin D1 mRNA are consistently found in malignant B cell proliferations with t(11;14).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0923-7534
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
567-70
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8573535-Antigens, Neoplasm,
pubmed-meshheading:8573535-Blotting, Western,
pubmed-meshheading:8573535-Cyclin D1,
pubmed-meshheading:8573535-Cyclins,
pubmed-meshheading:8573535-Diagnosis, Differential,
pubmed-meshheading:8573535-Flow Cytometry,
pubmed-meshheading:8573535-Gene Expression,
pubmed-meshheading:8573535-Humans,
pubmed-meshheading:8573535-Immunohistochemistry,
pubmed-meshheading:8573535-Lymphoma, Non-Hodgkin,
pubmed-meshheading:8573535-Lymphoproliferative Disorders,
pubmed-meshheading:8573535-Oncogene Proteins,
pubmed-meshheading:8573535-Retrospective Studies
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pubmed:year |
1995
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pubmed:articleTitle |
Cyclin D1 protein expression in mantle cell lymphoma.
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pubmed:affiliation |
Department of Pathology, University of South Florida, H. Lee Moffitt Cancer Center, Tampa, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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