Linked Life Data

857090

Source:http://linkedlifedata.com/resource/pubmed/id/857090

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-6-22
pubmed:abstractText
A procedure was developed for performing multiple-wash, saline, bronchopulmonary lavages in living small animals. Animals were anesthetized with halothane in oxygen, intubated with tracheal catheters made from intravenous cannulas, and maintained on a flow-through anesthetic system which allowed positive pressure ventilation and fluid instillation. Wash volumes were calculated from lung pressure-volume measurements of individual animals, and lavages were accomplished by instillation and withdrawal of four washes of warmed saline. Wash volume for the mouse, gerbil, hamster, rat, guinea pig, and rabbit ranged from 0.7 ml for the mouse to 31 ml for the rabbit. The percent of wash fluid recovered ranged from 73% for the rabbit to 90% for the rat. Cell recovery data for the hamster, rat, guinea pig, and rabbit were related to body size with the hamster having the lowest count and the rabbit the highest count. The mouse, hamster, and rabbit tolerated the procedure well, but evidence of lung damage was found in the rat, guinea pig, and gerbil. Cell recovery was similar to that reported for lavages of excised lungs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0023-6764
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
255-61
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Bronchopulmonary lavage of small laboratory animals.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.