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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8997
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pubmed:dateCreated |
1996-3-1
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pubmed:abstractText |
The glutathione S-transferases (GST) mediate exposure to various cytotoxic and genotoxic agents, including those associated with increased risk of the myelodysplastic syndromes (MDS). Both GST M1 (GSTM1) and GST theta 1 (GSTT1) genes have a "null" variant allele, in which the entire gene is absent. We tested whether the homozygous null genotype of GSTM1 and GSTT1 altered the risk for MDS.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
|
pubmed:issn |
0140-6736
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
347
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8569364-Case-Control Studies,
pubmed-meshheading:8569364-DNA,
pubmed-meshheading:8569364-Female,
pubmed-meshheading:8569364-Genotype,
pubmed-meshheading:8569364-Glutathione Transferase,
pubmed-meshheading:8569364-Humans,
pubmed-meshheading:8569364-Male,
pubmed-meshheading:8569364-Middle Aged,
pubmed-meshheading:8569364-Myelodysplastic Syndromes,
pubmed-meshheading:8569364-Odds Ratio,
pubmed-meshheading:8569364-Polymerase Chain Reaction,
pubmed-meshheading:8569364-Risk
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pubmed:year |
1996
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pubmed:articleTitle |
Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defect.
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pubmed:affiliation |
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.
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pubmed:publicationType |
Journal Article,
Multicenter Study
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