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| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0024880 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0118890 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0205615 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0162788 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C1514485 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C2346714 | lld:lifeskim |
| pubmed-article:8562971 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8562971 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8562971 | pubmed:dateCreated | 1996-3-1 | lld:pubmed |
| pubmed-article:8562971 | pubmed:abstractText | Although GATA-binding transcription factors (GATA-1 and GATA-2) are strongly expressed in cultured mast cells (CMCs), their expression in mast cells within tissues has not been reported. We examined the expression of GATA-1 and GATA-2 in skin tissues of mice using Northern blot analysis and in situ hybridization. mRNA for GATA-2 but not for GATA-1 was expressed in skin mast cells of WB-+/+ embryos between days 15 and 17 postcoitum (pc). The expression was downregulated on and after day 18 pc. Skin mast cells did not express GATA-2 after birth either. When the number of skin mast cells was compared with the number of GATA-2 mRNA-expressing cells, GATA-2 mRNA appeared to be expressed by mast cells only when the number was increasing. When the mRNA expression of high-affinity IgE receptor beta-subunit and mast cell carboxypeptidase A was used as differentiation markers, the expression of these mRNAs continued even after the downregulation of GATA-2 expression. To clarify the relationship of the proliferation and GATA-2 expression, proliferating CMCs derived from WBB6F1-+/+ mice were transplanted into the peritoneal cavity of mast cell-deficient WBB6F1-W/Wv mice. The CMCs stopped both the proliferation and GATA-2 expression after the transplantation, suggesting the association of these two parameters in mast cells within tissues of mice. | lld:pubmed |
| pubmed-article:8562971 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8562971 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8562971 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8562971 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8562971 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8562971 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:8562971 | pubmed:author | pubmed-author:YamamotoMM | lld:pubmed |
| pubmed-article:8562971 | pubmed:author | pubmed-author:KitamuraYY | lld:pubmed |
| pubmed-article:8562971 | pubmed:author | pubmed-author:NomuraSS | lld:pubmed |
| pubmed-article:8562971 | pubmed:author | pubmed-author:XuZZ | lld:pubmed |
| pubmed-article:8562971 | pubmed:author | pubmed-author:MizunoHH | lld:pubmed |
| pubmed-article:8562971 | pubmed:author | pubmed-author:JippoTT | lld:pubmed |
| pubmed-article:8562971 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8562971 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:8562971 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:8562971 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8562971 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8562971 | pubmed:pagination | 993-8 | lld:pubmed |
| pubmed-article:8562971 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8562971 | pubmed:meshHeading | pubmed-meshheading:8562971-... | lld:pubmed |
| pubmed-article:8562971 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8562971 | pubmed:articleTitle | Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. | lld:pubmed |
| pubmed-article:8562971 | pubmed:affiliation | Department of Pathology, Osaka University Medical School, Japan. | lld:pubmed |
| pubmed-article:8562971 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8562971 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8562971 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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