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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1977-6-11
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pubmed:abstractText |
The phospholipid monolayer technique has been used to study the transfer activity of the phospholipid exchange protein from beef brain. In measuring the transfer between a monolayer consisting of equimolar amounts of phosphatidylcholine and phosphatidylinositol and liposomes consisting of 98 mol% phosphatidylcholine and 2 mol% phosphatidylinositol, the beef brain protein demonstrates an 8-fold higher transfer activity for phosphatidylinositol than for phosphatidylcholine. Under similar conditions the phosphatidylcholine exchange protein from beef liver showed a great preference for phosphatidylcholine. Phosphatidylcholine liposomes devoid of phosphatidylinositol still functioned as receptors of phosphatidylinositol when the beef brain exchange protein was present. This indicates that this protein can catalyse a net transfer of phosphatidylinopsitol. Binding of both phosphatidylinositol and phosphatidylcholine to the beef brain protein was shown.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
466
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
10-22
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pubmed:dateRevised |
2006-4-17
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pubmed:meshHeading |
pubmed-meshheading:856266-Animals,
pubmed-meshheading:856266-Biological Transport,
pubmed-meshheading:856266-Brain,
pubmed-meshheading:856266-Cattle,
pubmed-meshheading:856266-Membranes, Artificial,
pubmed-meshheading:856266-Models, Biological,
pubmed-meshheading:856266-Nerve Tissue Proteins,
pubmed-meshheading:856266-Phosphatidylcholines,
pubmed-meshheading:856266-Phosphatidylinositols,
pubmed-meshheading:856266-Protein Binding
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pubmed:year |
1977
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pubmed:articleTitle |
The protein-mediated net transfer of phosphatidylinositol in model systems.
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pubmed:publicationType |
Journal Article
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