Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-2-13
pubmed:abstractText
Three seronegative sheep persistently infected with Border disease virus and six seropositive, non-viraemic sheep were examined for the cellular distribution of the agent. These animals originated from a closed flock which had been kept in an isolation facility for 5 years. They were killed and immediately necropsied. There were no gross abnormalities other than reduced body weight of the persistently infected sheep. Two samples of each major organ were collected. The first sample was fixed by immersion in formalin and processed for histological examination, which showed no lesions unequivocally attributable to the viral infection. The second sample was snap-frozen for immunohistochemical examination. This revealed viral antigen in all organs of the persistently infected, but in none of the seropositive animals. The infected cells included smooth muscle cells of hollow organs and blood vessels, epithelial cells of the alimentary tract and urogenital organs, lymphocytes in lymphoid organs, endocrine cells, neurons and glial cell.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0021-9975
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-200
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed-meshheading:8543676-Animals, pubmed-meshheading:8543676-Antigens, Viral, pubmed-meshheading:8543676-Body Weight, pubmed-meshheading:8543676-Border Disease, pubmed-meshheading:8543676-Border disease virus, pubmed-meshheading:8543676-Central Nervous System, pubmed-meshheading:8543676-Endocrine Glands, pubmed-meshheading:8543676-Epithelium, pubmed-meshheading:8543676-Female, pubmed-meshheading:8543676-Immunohistochemistry, pubmed-meshheading:8543676-Lymphocytes, pubmed-meshheading:8543676-Male, pubmed-meshheading:8543676-Mesencephalon, pubmed-meshheading:8543676-Muscle, Smooth, pubmed-meshheading:8543676-Neuroglia, pubmed-meshheading:8543676-Neurons, pubmed-meshheading:8543676-Rumen, pubmed-meshheading:8543676-Sheep, pubmed-meshheading:8543676-Spinal Cord, pubmed-meshheading:8543676-Trigeminal Ganglion
pubmed:year
1995
pubmed:articleTitle
An immunohistochemical study of the distribution of border disease virus in persistently infected sheep.
pubmed:affiliation
Institute of Veterinary Pathology, University of Zürich, Switzerland.
pubmed:publicationType
Journal Article