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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1996-1-24
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pubmed:abstractText |
To review the overall performance of a neonatal screening program for cystic fibrosis (CF) from 1981 to 1994, and to compare two strategies of case detection. PROGRAM DESIGN: Initially, immunoreactive trypsin (IRT) was measured in dried blood spots, and because of the low sensitivity of this test at days 3 to 5, a second sample was needed from babies with positive test results. Since 1993 a positive IRT assay result has been followed by direct gene analysis for the common CF mutation, delta F508, with the use of the same sample. Cases with false-negative results were actively sought throughout the period.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-3476
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
965-70
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8523199-Australia,
pubmed-meshheading:8523199-Clinical Protocols,
pubmed-meshheading:8523199-Cystic Fibrosis,
pubmed-meshheading:8523199-DNA Probes,
pubmed-meshheading:8523199-Heterozygote Detection,
pubmed-meshheading:8523199-Homozygote,
pubmed-meshheading:8523199-Humans,
pubmed-meshheading:8523199-Incidence,
pubmed-meshheading:8523199-Infant,
pubmed-meshheading:8523199-Infant, Newborn,
pubmed-meshheading:8523199-Mutagenesis,
pubmed-meshheading:8523199-Neonatal Screening,
pubmed-meshheading:8523199-Point Mutation,
pubmed-meshheading:8523199-Prognosis,
pubmed-meshheading:8523199-Retrospective Studies,
pubmed-meshheading:8523199-Trypsin
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pubmed:year |
1995
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pubmed:articleTitle |
Neonatal screening for cystic fibrosis: a comparison of two strategies for case detection in 1.2 million babies.
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pubmed:affiliation |
New South Wales Newborn Screening Program, Royal Alexandra Hospital for Children, Sydney, Australia.
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pubmed:publicationType |
Journal Article
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