Linked Life Data

8510195

Source:http://linkedlifedata.com/resource/pubmed/id/8510195

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-7-13
pubmed:abstractText
Thirty-two patients with extracapsular invasive prostatic adenocarcinoma were analysed to investigate the prognostic significance of DNA flow cytometry by using the nuclear material extracted from paraffin embedded prostatectomy specimens. The DNA ploid pattern was diploid in 61% of the tumors and aneuploid in 39%. A significant correlation between the DNA diploid pattern with pathologic low grade tumors and the DNA aneuploid pattern with high stage tumors was not proved. The clinical stage correlated well with patients survival but only DNA ploidy pattern and pathologic grade had trends of correlation. However, if only the stage D tumors were analysed, a significant prognostic predictive value of DNA flow cytometry was identified. Although the results maybe regarded as preliminary, (in view of the small number of patients), these suggest that DNA content from the initial surgical samples provide only a synergistic effect to the clinical stage and pathologic grade in the prognostic evaluation of the advanced prostate cancers especially for those who underwent hormonal therapy postoperatively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0257-5655
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
122-30
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Flow cytometric DNA analysis of advanced prostatic adenocarcinoma.
pubmed:affiliation
Department of Urology, Kaohsiung Medical College, Taiwan, Republic of China.
pubmed:publicationType
Journal Article