Linked Life Data

849745

Source:http://linkedlifedata.com/resource/pubmed/id/849745

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-5-27
pubmed:abstractText
1. We found that a single injection of 17beta-estradiol into immature chicks resulted within 24 h in a 2-fold increase of the transcripitional capacity of liver nuclei which involved both endogenous RNA polymerase I and II actvities. Similarly, RNA polymerase activity I of purified nucleoli was also doubled. 2. During purification of RNA polymerase I from controls and treated chicks the difference in activity was almost completely lost. 3. RNA polymerase I could be resolved into two forms, IA and IB, on CM-Spehadex. Form IA increased and form IB decreased after estrogen treatment while the sum of the two remained constant. Form IA sedimented more slowly than form IB in glycerol gradients and was predominant in purified nucleoli. 4. These observations suggest that there may be an equilibrium between the two forms of RNA polymerase I which may change in order to produce the translational shift-up which occurs after estrogen treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0014-2956
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
507-13
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Multiple forms of DNA-dependent RNA polymerase I from immature chick liver. Selective effect of 17beta-estradiol.
pubmed:publicationType
Journal Article