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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1993-5-25
|
| pubmed:abstractText |
Alcian blue and plumbagin induced transient Ca2+ release from fragmented sarcoplasmic reticulum. Dithiothreitol (DTT) and glutathione (GSH) partially blocked Ca2+ release induced by these oxidizing compounds. Pretreatment of alcian blue and plumbagin with DTT or GSH for more than 1 min was required to abolish the ability of the oxidizing compounds to release Ca2+. Mg2+ and ruthenium red completely blocked alcian blue-and plumbagin-induced Ca2+ release. These results suggest that oxidation of sulfhydryls on Ca2+ release channels induces Ca2+ release even in the presence of GSH in situ.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0014-4754
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
49
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
282-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8477832-Animals,
pubmed-meshheading:8477832-Calcium,
pubmed-meshheading:8477832-Dithiothreitol,
pubmed-meshheading:8477832-Glutathione,
pubmed-meshheading:8477832-Oxidation-Reduction,
pubmed-meshheading:8477832-Rana catesbeiana,
pubmed-meshheading:8477832-Sarcoplasmic Reticulum,
pubmed-meshheading:8477832-Sulfhydryl Compounds
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Sulfhydryl oxidation induces calcium release from fragmented sarcoplasmic reticulum even in the presence of glutathione.
|
| pubmed:affiliation |
Department of Physiology, Nagoya City University Medical School, Japan.
|
| pubmed:publicationType |
Journal Article,
In Vitro
|