Linked Life Data

8464360

Source:http://linkedlifedata.com/resource/pubmed/id/8464360

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-5-6
pubmed:abstractText
19F NMR imaging of the perfluorocarbon emulsion Fluosol has been used to study regional variations in oxygen tension in rat liver and spleen. We have used the linear dependence of spin lattice relaxation rate (1/T1) on the partial oxygen pressure (pO2) of Fluosol to determine the oxygen tension in the reticuloendothelial system (RES) of the liver and spleen of male Sprague-Dawley rats which have received serial infusions of Fluosol. Oxygen tension maps have been computed from 19F NMR images using a calibration obtained for Fluosol in vitro at 37.5 degrees C. The spatial resolution of the pO2 maps computed using this technique is 1.2 x 1.2 mm in 3-mm thick slices. Calculations from in vivo pO2 maps indicate an average change in the median pO2 of the RES from 118 to 80 mmHg for (n = 7) rats breathing 95% O2 and 5% CO2 (carbogen) and air, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0740-3194
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
446-58
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Imaging oxygen tension in liver and spleen by 19F NMR.
pubmed:affiliation
Yale University School of Medicine, Department of Diagnostic Radiology, New Haven, CT 06510.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't