Linked Life Data

8458819

Source:http://linkedlifedata.com/resource/pubmed/id/8458819

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-4-27
pubmed:abstractText
We evaluated the contribution of measurement errors in PO2 to the discrepancy between the intrapulmonary shunt values simultaneously obtained by the conventional O2 method (O2-shunt) and the multiple inert gas elimination technique (IG-shunt). Excised left lower lobes of dogs were perfused at a constant flow and ventilated at constant volume. Variable degrees of intrapulmonary shunt were created by O2 absorption while the lobes were collapsed. IG-shunt ranged from 0 to 66%. Although the O2-shunt and IG-shunt values correlated well (r = 0.97), the slope was only 0.74 and the regression line crossed the line of identity at 12% IG-shunt. The gas-to-blood ratio of the oxygen electrode was constant over the range 80-687 Torr and therefore did not seem to be an important factor in the shunt discrepancy. Errors due to nonlinearity of the O2 electrode also had only a minor effect. However, PO2 history of the electrode just before injection of blood samples into the cuvette had a profound and complex effect on the measured PO2. We conclude that PO2 electrode hysteresis can be a major factor in the wide variability of PO2 measurements and could account for most of the differences between our O2-shunt and IG-shunt data.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
8750-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
951-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Intrapulmonary shunt in excised dog lobes: comparison of oxygen and inert gas methods.
pubmed:affiliation
First Department of Internal Medicine, Yamagata University School of Medicine, Japan.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, U.S. Gov't, P.H.S.