Linked Life Data

8452270

Source:http://linkedlifedata.com/resource/pubmed/id/8452270

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-4-9
pubmed:abstractText
To assess the evolution of satisfactory neohepatic graft function or failure, hemodynamic variables, along with data for oxygen delivery and utilization, were analyzed retrospectively in 99 patients undergoing orthotopic liver transplantation. Caval cross-clamping without venovenous bypass initiated a series of hemodynamic events, characterized by decreases in pulmonary artery pressures, cardiac output, and arterial pressures and increases in systemic vascular resistance, with reciprocal changes after unclamping. Concerning oxygen transport, the increased oxygen delivery after caval unclamping led to increases of mixed venous oxygen tension, decreases of oxygen extraction, and the arteriovenous oxygen content difference. The most striking result, however, was that with similar values for oxygen delivery, the patients with primary nonfunction (n = 9) had both lower anhepatic oxygen consumption, much smaller increases in oxygen consumption, and lower ratios of oxygen extraction during reperfusion of the liver than the patients with normal initial graft function (n = 90). Thus, distinct increases in total body oxygen consumption were found to be indicative of the onset of hepatocellular function and satisfactory neohepatic graft function. The authors conclude that perioperative measurements of whole-body oxygen consumption are important in reflecting early allograft viability during orthotopic liver transplantation without anhepatic venovenous bypass.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0003-2999
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
574-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Perioperative liver graft function: the role of oxygen transport and utilization.
pubmed:affiliation
Department of Anesthesia and General Intensive Care, University of Vienna, Austria.
pubmed:publicationType
Journal Article