Linked Life Data

8447967

Source:http://linkedlifedata.com/resource/pubmed/id/8447967

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-4-15
pubmed:abstractText
Prenatal alcohol exposure is associated with a variety of developmental abnormalities, including neuroanatomical, physical, and behavioral features. Several mechanisms for alcohol's teratogenic effects have been proposed. This study addresses the role of prostaglandins in the abnormal development that often occurs after maternal alcohol consumption. On gestation days 8 to 18, pregnant Sprague-Dawley rats were prenatally treated with 6 g/kg alcohol following pretreatment with 150 mg/kg aspirin. Behavioral testing of offspring included measures of open-field activity, exploratory behavior, passive avoidance, active avoidance, and acoustic startle response. In most cases, pretreatment with aspirin did not affect performance in alcohol-exposed or control rats.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0741-8329
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
The behavioral teratogenicity of alcohol is not affected by pretreatment with aspirin.
pubmed:affiliation
SDSU/UCSD Joint Doctoral Program in Clinical Psychology, Department of Psychology, San Diego, CA 92120.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.