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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1993-3-30
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pubmed:abstractText |
The role of anti-rotavirus fecal IgA (RVflgA) in protecting children against natural rotavirus infections is unclear. Rotavirus outbreaks occurred in each of four day care centers attended by 129 children; 42% of the infections were asymptomatic. RVflgA titers were measured by EIA before infection and 4 weeks later in 50 children who excreted rotavirus (excretors) and in two samples 4 weeks apart from 50 children without detected virus excretion (nonexcretors). Forty-three (86%) excretors and 18 (36%) nonexcretors had a fourfold or greater RVflgA titer rise. Preexposure RVflgA titers were higher in not infected than symptomatic (P = .002), asymptomatic than symptomatic (P = .036), and not infected than asymptomatic children (P = .07). RVflgA titers after asymptomatic infections were slightly than after symptomatic infections (P = .087). In summary, higher RVflgA titers were associated with protection against infection and illness and increased fourfold or more in both asymptomatic and symptomatic children.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
167
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
577-83
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8440929-Age Factors,
pubmed-meshheading:8440929-Analysis of Variance,
pubmed-meshheading:8440929-Antibodies, Viral,
pubmed-meshheading:8440929-Case-Control Studies,
pubmed-meshheading:8440929-Child Day Care Centers,
pubmed-meshheading:8440929-Diarrhea, Infantile,
pubmed-meshheading:8440929-Disease Outbreaks,
pubmed-meshheading:8440929-Feces,
pubmed-meshheading:8440929-Humans,
pubmed-meshheading:8440929-Immunoglobulin A,
pubmed-meshheading:8440929-Infant,
pubmed-meshheading:8440929-Longitudinal Studies,
pubmed-meshheading:8440929-Rotavirus Infections,
pubmed-meshheading:8440929-Serotyping
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pubmed:year |
1993
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pubmed:articleTitle |
Fecal antibody responses to symptomatic and asymptomatic rotavirus infections.
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pubmed:affiliation |
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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