Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1977-5-12
|
| pubmed:abstractText |
The locomotion of human neutrophils is modelled by a continuous-time Markov chain model consisting of five states: state O, where the cell is stationary, and four motile states whose directions are defined by the four quadrants of a Cartesian plane. In this paper, the Markov property is verified experimentally in special cases. Further experimental evidence for the model is provided by the waiting-time distributions in each of the five states, which are well approximated by exponential distributions. Using the steady-state distribution of the Markov chain as a measure of the ultimate motion of the cells, it is possible to detect the effect of known chemotactic agents upon neutrophil locomotion. Other useful parameters describing neutrophil locomotion are presented.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0008-4212
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:843984-Cell Movement,
pubmed-meshheading:843984-Chemotaxis,
pubmed-meshheading:843984-Humans,
pubmed-meshheading:843984-Markov Chains,
pubmed-meshheading:843984-Models, Biological,
pubmed-meshheading:843984-Neutrophils,
pubmed-meshheading:843984-Probability,
pubmed-meshheading:843984-Time Factors
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
A Markov chain characterization of human neutrophil locomotion under neutral and chemotactic conditions.
|
| pubmed:publicationType |
Journal Article
|