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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1993-3-23
|
| pubmed:abstractText |
Male rats at six different ages received diazepam on a 4-day treatment schedule. Cross-tolerance to hexobarbital was tested several times during withdrawal period with an anaesthesia threshold technique. Pattern of cross-tolerance was different at different ages. Thus, age and maturation of the rat is a variable which must be considered in studies of tolerance to diazepam.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0006-8993
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
600
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
345-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8435757-Aging,
pubmed-meshheading:8435757-Animals,
pubmed-meshheading:8435757-Diazepam,
pubmed-meshheading:8435757-Drug Tolerance,
pubmed-meshheading:8435757-Electroencephalography,
pubmed-meshheading:8435757-Hexobarbital,
pubmed-meshheading:8435757-Male,
pubmed-meshheading:8435757-Rats,
pubmed-meshheading:8435757-Rats, Sprague-Dawley,
pubmed-meshheading:8435757-Substance Withdrawal Syndrome
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Maturation-related changes in tolerance development to hexobarbital after short term treatment with diazepam in the rat.
|
| pubmed:affiliation |
Department of Pharmacology, University of Umeå, Sweden.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|