Linked Life Data

8427870

Source:http://linkedlifedata.com/resource/pubmed/id/8427870

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-3-10
pubmed:abstractText
The effect of ethanol on polyamine acetylation was studied in rat liver. Animals were fed on nutritionally complete liquid diets with 36% or 12% of total calories supplied as ethanol or isocaloric carbohydrates for 4 months. The diet with 36% calories as ethanol significantly increased the activity of cytosolic spermidine/spermine N1-acetyltransferase, the rate-limiting enzyme in polyamine interconversion. Such a stimulation did not appear in rats under the 12% ethanol regimen. The stimulation of spermidine/spermine N1-acetyltransferase was associated with increases in putrescine and spermidine concentrations, an appearance of N1-acetylspermidine, and a decrease in spermine. These results suggest that chronic ethanol intake stimulates the acetylation of polyamines and their interconversion in rat liver.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
1156
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Polyamine acetylation in rat liver following long-term ethanol ingestion.
pubmed:affiliation
Centro di Studio sulla Patologia Cellulare, C.N.R., Università di Milano, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't