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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1993-3-1
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| pubmed:abstractText |
The aim of this study was to determine whether the greater ventilation in children at rest and during exercise is related to a greater CO2 ventilatory response. The CO2 ventilatory response was measured in nine prepubertal boys [10.3 years (SD 0.1)] and in 10 adults [24.9 years (SD 0.8)] at rest and during moderate exercise (VCO2 = 20 ml.kg-1.min-1) using the CO2-rebreathing method. Three criteria were measured in all subjects to assess the ventilatory response to CO2: the CO2 sensitivity threshold (Th), which was defined as the value of end tidal PCO2 (PETCO2) where the ventilation increased above its steady-state level; the reactivity slope expressed per unit of body mass (SBM), which was the slope of the linear relation between minute ventilation (VE) and PETCO2 above Th; and the slope of the relationship between the quotient of tidal volume (VT) and inspiration time (tI) and PETCO2 (VT.tI-1.PETCO2(-1)) values above Th. The VE, VT, breathing frequency (fR), oxygen uptake (VO2), and CO2 production (VCO2) were also measured before the CO2-rebreathing test. The following results were obtained. First, children had greater ventilation per unit body weight than adults at rest (P < 0.001) and during exercise (P < 0.01). Second, at rest, only VT.tI-1.PETCO2(-1) was greater in children than in adults (P < 0.001). Third, during exercise, children had a higher SBM (P < 0.02) and VT.tI-1.PETCO2(-1) (P < 0.001) while Th was lower (P < 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
0301-5548
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
66
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
25-30
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading | |
| pubmed:year |
1993
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| pubmed:articleTitle |
Ventilatory response of prepubertal boys and adults to carbon dioxide at rest and during exercise.
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| pubmed:affiliation |
Service d'Exploration Fonctionelle Respiratoire, Hôpital Aiguelongue, Montpellier, France.
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| pubmed:publicationType |
Journal Article
|