rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1993-3-3
|
pubmed:abstractText |
The beta-myosin heavy chain (beta-MHC) gene has been identified as a major locus for familial hypertrophic cardiomyopathy (FHCM). We recently showed that one of the common mutations associated with FHCM is expressed in the cardiac muscle messenger RNA (mRNA) of an affected individual. Since beta-MHC is a major sarcomeric protein of cardiac and skeletal muscle, studies were performed to determine whether the mutation is also expressed in skeletal muscle.
|
pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0009-7322
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
87
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
406-12
|
pubmed:dateRevised |
2010-3-24
|
pubmed:meshHeading |
pubmed-meshheading:8425289-Adult,
pubmed-meshheading:8425289-Alleles,
pubmed-meshheading:8425289-Base Sequence,
pubmed-meshheading:8425289-Cardiomyopathy, Hypertrophic,
pubmed-meshheading:8425289-DNA,
pubmed-meshheading:8425289-Humans,
pubmed-meshheading:8425289-Middle Aged,
pubmed-meshheading:8425289-Molecular Probes,
pubmed-meshheading:8425289-Molecular Sequence Data,
pubmed-meshheading:8425289-Muscles,
pubmed-meshheading:8425289-Mutation,
pubmed-meshheading:8425289-Papillary Muscles,
pubmed-meshheading:8425289-Polymerase Chain Reaction,
pubmed-meshheading:8425289-RNA, Messenger,
pubmed-meshheading:8425289-Reference Values,
pubmed-meshheading:8425289-Transcription, Genetic
|
pubmed:year |
1993
|
pubmed:articleTitle |
Hypertrophic cardiomyopathy mutation is expressed in messenger RNA of skeletal as well as cardiac muscle.
|
pubmed:affiliation |
Baylor College of Medicine, Houston, TX 77030.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|