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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-2-2
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pubmed:abstractText |
Previous studies have indicated that RNA levels for pi-class glutathione S-transferase (GST pi), a phase II, drug-metabolizing enzyme, were inversely related to estrogen receptor (ER) and progesterone receptor (PR) levels in human breast tumors. Because GST pi also is expressed in normal breast epithelium, an immunohistochemical assay that uses affinity-purified polyclonal antibodies to GST pi was developed to examine the possible relationship between GST pi expression in breast cancer cells and hormone receptor expression, as well as prognosis, in patients with primary breast cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0732-183X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
49-58
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8418241-Breast Neoplasms,
pubmed-meshheading:8418241-Female,
pubmed-meshheading:8418241-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:8418241-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:8418241-Glutathione Transferase,
pubmed-meshheading:8418241-Humans,
pubmed-meshheading:8418241-Isoenzymes,
pubmed-meshheading:8418241-Middle Aged,
pubmed-meshheading:8418241-Multivariate Analysis,
pubmed-meshheading:8418241-Pilot Projects,
pubmed-meshheading:8418241-Prognosis,
pubmed-meshheading:8418241-Receptors, Estrogen,
pubmed-meshheading:8418241-Receptors, Progesterone,
pubmed-meshheading:8418241-Survival Analysis
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pubmed:year |
1993
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pubmed:articleTitle |
A pilot study of pi-class glutathione S-transferase expression in breast cancer: correlation with estrogen receptor expression and prognosis in node-negative breast cancer.
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pubmed:affiliation |
Medicine Branch, National Cancer Institute, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article
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