Linked Life Data

841613

Source:http://linkedlifedata.com/resource/pubmed/id/841613

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-4-30
pubmed:abstractText
Antibiotics, erythromycin and a thiocarbamide derivative of erythromycin were tested for their ability to induce chromosome translocations in whole-body irradiated mice with a dose of 600 r. The aim of the present paper was to determine whether these antibiotics might induce by themselves, chromosomal translocations and whether these agents have a protective effect against X-rays-induced chromosomal translocations in the spermatocytes at the first meiotic metaphase. The incidence of translocations in irradiated animals was 9.07%; in animals treated with erythromycine after irradiation it was 3.80%; and in those treated with a thiocarbamide derivative of erythromycin following irradiation was 3.20%. Not a single chromosome rearrangement was scored among the non-irradiated animals, treated with the mentioned antibiotics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0039-2073
pubmed:author
pubmed:issnType
Print
pubmed:volume
153
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
200-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
The effect of erythromycin and its thiocarbamide derivative on the induction of meiotic chromosome rearrangements in irradiated male mice.
pubmed:publicationType
Journal Article