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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1993-10-22
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pubmed:abstractText |
Pulsed-field mapping of a number of DNA markers in the Pola-Zfx region of the mouse X chromosome has established a genomic restriction map extending over 1.4 Mb. A number of YAC clones from the Pola-Zfx region have been isolated from three mouse YAC libraries--first, a mouse C57BL/10 partial R1 YAC library constructed in a yeast strain carrying a rad52 mutation (Chartier et al. (1992) Nature Genetics 1: 132-136); second, a mouse C3H partial R1 library (Larin et al. (1991) Proc. Natl. Acad. Sci. USA 88: 4123-4127); and third, a mouse C57BL/6 partial R1 library (Burke et al. (1991) Mamm. Genome 1:65). Six YAC clones encompass the Zfx-Pola region, confirming the linkage of the Pola and Zfx loci and establishing a physical map order in this region of cen-Pola-DXCrc140-DXCrc57-Zfx-tel. The close linkage of Pola and Zfx in the mouse genome suggests that the POLA and ZFX loci must also be closely linked on the human X chromosome.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0888-7543
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
52-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8406471-Animals,
pubmed-meshheading:8406471-Base Sequence,
pubmed-meshheading:8406471-Chromosome Walking,
pubmed-meshheading:8406471-Chromosomes, Fungal,
pubmed-meshheading:8406471-DNA-Binding Proteins,
pubmed-meshheading:8406471-Electrophoresis, Gel, Pulsed-Field,
pubmed-meshheading:8406471-Female,
pubmed-meshheading:8406471-Gene Library,
pubmed-meshheading:8406471-Genetic Markers,
pubmed-meshheading:8406471-Genome, Human,
pubmed-meshheading:8406471-Humans,
pubmed-meshheading:8406471-Kruppel-Like Transcription Factors,
pubmed-meshheading:8406471-Male,
pubmed-meshheading:8406471-Mice,
pubmed-meshheading:8406471-Mice, Inbred C3H,
pubmed-meshheading:8406471-Mice, Inbred C57BL,
pubmed-meshheading:8406471-Molecular Sequence Data,
pubmed-meshheading:8406471-Restriction Mapping,
pubmed-meshheading:8406471-Transcription Factors,
pubmed-meshheading:8406471-X Chromosome
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pubmed:year |
1993
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pubmed:articleTitle |
YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.
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pubmed:affiliation |
Department of Biochemistry and Molecular Genetics, St. Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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