Linked Life Data

8396693

Source:http://linkedlifedata.com/resource/pubmed/id/8396693

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-10-13
pubmed:abstractText
Preganglionic stimulation of the thoracic sympathetic nerve trunk produced frequency-related decreases of ulnar arterial blood flow in the forepaw of anesthetized cats as measured by ultrasonic flowmetry. Vasoconstrictor responses were not altered by administration of propranolol or atropine. When given alone, both prazosin (3-100 micrograms/kg, i.v.) and rauwolscine (10-300 micrograms/kg, i.v.) produced only a modest reduction of sympathetic evoked vasoconstriction. However, extensive blockade was obtained when both antagonists were administered to the same animal. These results suggest that both alpha 1- and alpha 2-adrenoceptors coexist at postsynaptic sites in the vasculature of the cat paw and that neural activation of either type results in potent vasoconstriction.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0021-5198
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Postjunctional alpha 1- and alpha 2-adrenoceptors in cat forepaw vasculature.
pubmed:affiliation
Department of Pharmacology, University of Oklahoma College of Medicine, Oklahoma City 73190.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.