Linked Life Data

8394727

Source:http://linkedlifedata.com/resource/pubmed/id/8394727

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-9-17
pubmed:abstractText
An experimental animal models of nasal hypersensitive reaction had been developed in twelve guinea pigs by intranasal applications of 2.4-toluene diisocynate (TDI). Symptoms, morphological appearance of the nasal mucosal scrapings and tissue pathology were studied, and the histamine content in the turbinates evaluated. The results showed a typical picture of nasal hypersensitive reaction. A plenty of eosinophils and mast cells was found on the surface of the nasal mucosa. A marked infiltration of the eosinophils was seen not only in the subepithalial connective tissue but also in the epithelial layer and in the enlarged venous vessels. Significantly higher levels of histamine were detected in the mucosa from TDI treated animals than in control animals (P < 0.01). We consider the experimental models to be ideal.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0412-3948
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-8, 58-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Experimental models of nasal hypersensitive reaction].
pubmed:affiliation
First Affiliated Hospital, Bethune University of Medical Sciences, Changchun.
pubmed:publicationType
Journal Article, English Abstract