Linked Life Data

8384537

Source:http://linkedlifedata.com/resource/pubmed/id/8384537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
288
pubmed:dateCreated
1993-4-29
pubmed:abstractText
Cultured chondrocytes were bound to hydroxyapatite (HA) and implanted in surgically created bone defects in the ulna of the rabbit. Chondrocytes were obtained from the iliac crest cartilage of the rabbit and were cultured on the HA block for two weeks before implantation. Scanning electron micrographs showed that pores of the HA surface and the inside of the block were filled with cultured cells. After cultivation for two weeks, the expression of chondrocyte-specific characteristics was confirmed in these cells by an implanted diffusion of chondrocyte-specific characteristics was confirmed in these cells by an implanted diffusion chamber experiment. The HA without chondrocytes served as a control. At two weeks postimplantation, proliferating chondrocytes were observed on the surface and in the inside pores of the HA-chondrocyte blocks but not the HA controls. At four and six weeks postimplantation, in the central region of the implants, there was a significant increase in the amount of bone formation in the HA with cultured chondrocytes. At 13 weeks post-implantation, the implants were partially resorbed and completely enveloped in lamellar bone, including bone marrow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0009-921X
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-93
pubmed:dateRevised
2005-3-3
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Repair of bone defect with cultured chondrocytes bound to hydroxyapatite.
pubmed:affiliation
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Japan.
pubmed:publicationType
Journal Article