Linked Life Data

8375963

Source:http://linkedlifedata.com/resource/pubmed/id/8375963

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-10-21
pubmed:abstractText
Intravital microscopy (IVM) and laser-Doppler-flowmetry- or fluxmetry (LDF) were used to simultaneously assess periodic hemodynamics (vaso/flowmotion) in the tenuissimus muscle of eleven New Zealand White (NZW)-rabbits during local reduction of arterial pressure. Diameter changes of transverse arterioles (TR) were monitored with the microscope, and in six animals also blood cell velocity measurements were performed with a cross-correlation technique. One LDF was positioned at the tenuissimus muscle as close to the objective as possible without causing optical interference. A second LDF was positioned at the underlying gastrocnemius muscle. Slow wave vaso/flowmotion was not present at control arterial pressure (x = 73 mmHg, range-r: 60-87) but was induced as local femoral pressure was reduced, being minimal at 35 mmHg (r: 20-50). The vaso/flowmotion frequencies of the IVM, tenuissimus-LDF, and the gastrocnemius-LDF signals were in the order of 1.5 cpm. LDF-flowmotion frequencies in the two muscles showed no correlation (R = +0.06, P = 0.4). The IVM flow-frequencies in the TR, however, correlated well with the oscillations recorded with the tenuissimus-LDF placed nearby (R = +0.89, p +0.01). Regular diameter variations were recorded only in the eleven cases where the microscope focused on the proximal portion of the TR; these oscillation frequencies were correlated with corresponding LDF-tenuissimus recordings (R = +0.97, p < 0.01). We conclude that slow wave vasomotion in rabbit skeletal muscle is not present during control conditions, but is induced on a regular basis by local blood pressure reduction and that it originates in the proximal part of the TR as reflected by slow wave flowmotion in LDF.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0167-6865
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-97
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The vascular origin of slow wave flowmotion in skeletal muscle during local hypotension.
pubmed:affiliation
Department of Applied Mechanics and Engineering Sciences-Bioengineering, University of California, San Diego, La Jolla.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't