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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1993-10-8
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pubmed:abstractText |
The fatty acid profiles and total lipid contents of two skeletal muscles, adipose tissue, heart, liver and kidney of swine fed a diet rich in omega 3 (n-3) fatty acids (i.e., 5% fish oil) was investigated. These values were compared to those determined for animals which were fed an equal caloric diet low in n-3 fatty acids (i.e., 5% coconut oil). All supplementations were given over a 13-week period. The lipids were extracted with chloroform-methanol, trans-esterified and the relative fatty acid methyl-esters concentrations were determined using capillary gas chromatography. The fish oil diet significantly enhanced the relative amounts of n-3 fatty acids (i.e., eicosapentaenoic acid and docosahexaenoic acid) in all tissues examined. In the heart, liver and kidney, the increases in n-3 fatty acids were compensated by decreases primarily in arachidonic acid, but in the other tissues the contents of lauric and myristic acids were also reduced. In general, the n-3 fatty acid contents were 40-165% higher in the animals fed the fish oil. Supplementation of n-3 fatty acids in swine induced a significant incorporation of these fatty acids throughout the body, however the extent of this incorporation differed between tissues perhaps due to tissue-specific metabolic pathways.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats, Unsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Docosahexaenoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Eicosapentaenoic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Omega-3,
http://linkedlifedata.com/resource/pubmed/chemical/Fish Oils,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Oils,
http://linkedlifedata.com/resource/pubmed/chemical/coconut oil
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-6807
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
134-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8373137-Adipose Tissue,
pubmed-meshheading:8373137-Animals,
pubmed-meshheading:8373137-Arachidonic Acid,
pubmed-meshheading:8373137-Dietary Fats, Unsaturated,
pubmed-meshheading:8373137-Docosahexaenoic Acids,
pubmed-meshheading:8373137-Eicosapentaenoic Acid,
pubmed-meshheading:8373137-Fatty Acids,
pubmed-meshheading:8373137-Fatty Acids, Omega-3,
pubmed-meshheading:8373137-Fish Oils,
pubmed-meshheading:8373137-Heart,
pubmed-meshheading:8373137-Kidney,
pubmed-meshheading:8373137-Liver,
pubmed-meshheading:8373137-Male,
pubmed-meshheading:8373137-Muscles,
pubmed-meshheading:8373137-Myocardium,
pubmed-meshheading:8373137-Plant Oils,
pubmed-meshheading:8373137-Swine
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pubmed:year |
1993
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pubmed:articleTitle |
A high omega 3 fatty acid diet alters fatty acid composition of heart, liver, kidney, adipose tissue and skeletal muscle in swine.
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pubmed:affiliation |
Experimental Station Thalhausen, Technical University of Munich, FRG.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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