|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1993-10-7
|
|
pubmed:abstractText |
Pregnant females are susceptible to intracellular pathogens and are biased towards humoral rather than cell-mediated immunity. Since TH1 cytokines compromise pregnancy and TH2 cytokines are produced at the maternal-fetal interface, we hypothesize that these TH2 cytokines inhibit TH1 responses, improving fetal survival but impairing responses against some pathogens.
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|
pubmed:commentsCorrections |
|
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pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0167-5699
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
353-6
|
|
pubmed:dateRevised |
2005-11-16
|
|
pubmed:meshHeading |
pubmed-meshheading:8363725-Animals,
pubmed-meshheading:8363725-Cytokines,
pubmed-meshheading:8363725-Embryonic and Fetal Development,
pubmed-meshheading:8363725-Female,
pubmed-meshheading:8363725-Humans,
pubmed-meshheading:8363725-Killer Cells, Natural,
pubmed-meshheading:8363725-Maternal-Fetal Exchange,
pubmed-meshheading:8363725-Mice,
pubmed-meshheading:8363725-Pregnancy,
pubmed-meshheading:8363725-T-Lymphocytes, Helper-Inducer
|
|
pubmed:year |
1993
|
|
pubmed:articleTitle |
Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?
|
|
pubmed:affiliation |
Dept of Immunology, University of Alberta, Edmonton, Canada.
|
|
pubmed:publicationType |
Journal Article,
Review
|
