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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1993-9-29
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pubmed:abstractText |
A New method for the detection of lupus anticoagulant was developed. Plasma factor V activities using tissue thromboplastin (simplastin auto-SA) and partial thromboplastin (platelin excel LS-LS) were measured simultaneously. Furthermore, the ratio of the two activities was calculated (SA/LS ratio) as a marker of lupus anticoagulant. The normal range of SA/LS ratio was 0.79-1.39 (mean +/- 3SD). The high SA/LS ratios were detected in all of 15 patients with positive lupus anticoagulant, in 3 (5.8%) of 52 SLE patients with normal activated partial thromboplastin time, in 2 (28.7%) of 7 patients with hemophilia, in 1 (33.3%) of 3 patients with factor VIII inhibitor and in 4 (3.3%) of 122 patients with various diseases, respectively. All of 15 patients with liver dysfunction, 54 patients under warfarin treatment and 8 patients under heparin treatment had normal SA/LS ratio.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0047-1860
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
713-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8361039-Factor V,
pubmed-meshheading:8361039-Female,
pubmed-meshheading:8361039-Hemophilia A,
pubmed-meshheading:8361039-Humans,
pubmed-meshheading:8361039-Lupus Coagulation Inhibitor,
pubmed-meshheading:8361039-Lupus Erythematosus, Systemic,
pubmed-meshheading:8361039-Male,
pubmed-meshheading:8361039-Methods,
pubmed-meshheading:8361039-Reference Values
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pubmed:year |
1993
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pubmed:articleTitle |
[Newly developed method by the use of factor Y assay for the detection of the lupus anticoagulant].
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pubmed:affiliation |
Department of Laboratory Medicine, Gunma University, School of Medicine, Maebashi.
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pubmed:publicationType |
Journal Article,
English Abstract
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